ApiJect experts share knowledge and know-how to deliver innovative solutions customized to achieve our customer's goals and objectives.
Global Manufacturing Supply Chain Resiliency
We have created a compact and flexible supply chain that can be almost entirely domestic in major markets. This is because we rely on two robust manufacturing technologies to make our platform: Blow-Fill-Seal (BFS) aseptic filling and plastic injection molding.
BFS Temperature Management
Our BFS manufacturing experts employ a variety of techniques to consistently manage the drug product’s temperature throughout the fill-finish process.
Our experts marry the efficiency and flexibility of BFS with attachable plastic components to create drug delivery systems. This approach has the potential to enable scalable and efficient manufacturing of single-dose prefilled syringe which can typically only be found in multi-dose presentations.
Partnering: Pharmaceutical Companies
We help pharma companies fill-finish sterile liquids by working together to create BFS based, prefilled drug delivery systems, and then assist in the fill-finish process. The result is a prefilled drug delivery system that can be flexibly manufactured at various facilities that use BFS.
ApiJect Company Profile
ApiJect is a medical technology company that seeks to improve how companies fill-finish injectable medicines. We do this by working with pharma partners to design rapidly-scalable drug delivery systems, and assist in manufacturing those devices at their facilities or a trusted CMO/CDMO.
What Have Been the Biggest Surprises with COVID-19?
with Ed Kelley, PhD, Chief Global Health Officer
The pandemic’s effects have been far more wide-reaching than many health officials expected, but COVID has also accelerated some positive trends.
Advances in Sterile Liquids Packaging and Form Factors
with Jon Burgess, Packaging Engineer
Discussion on packaging factors that have led to wider acceptance of Blow-Fill-Seal technology in the pharmaceutical industry.
Strengths of Diversity in Pharma
with Amy Stewart, Chief People Officer
Companies are realizing that a strong commitment to DEI and ESG attracts employees. Word of mouth is very powerful. Companies want to do business with partners that are inclusive with positive values and environmental initiatives.
The Surprising Strengths of Blow-Fill-Seal
with Philip Leslie, Acting Head of Manufacturing
Why does the FDA calls BFS an “advanced aseptic process”? How does BFS combine high-speed, economically efficient production with notable manufacturing flexibility? Respected industry veteran Philip Leslie explains “the basics of BFS.”
BFS Covers Injectables and Vaccines, Too
with Ray Sell, Vice President, Business Development
BFS drug delivery systems go far beyond ophthalmic and oral solutions; BFS is also used to fill-finish injectables and vaccines.
The Heat Factor: Part 1 & 2:Why it Matters in Blow-Fill-Seal
with Jeff Price, Consulting Principal BFS Engineer
At ApiJect, our engineers have taken these filling enhancements even further by developing proprietary temperature control management methods that can potentially enable many temperature sensitive biologics and vaccines that are not possible on standard BFS lines.
Single-Dose Drug Delivery Fill-Finish Facility that is Scalable, Flexible, and able to Deliver up to 45M Units Per Month Delivered within an Accelerated Timeline of Fewer Than 7 Months
Part 3 of Pharmaceutical Technology Post-Webinar Series
ApiJect committed to creating emergency temporary fill-finish capacity for up to 45M doses a month of a candidate COVID-19 vaccine on BFS lines by the end of 2020. All of these BFS-packaged doses could then be used, if necessary, in ApiJect Prefilled Injectors for scalable, single-dose delivery.
Solving Drug Challenges with Innovation, BFS, and a Technology Platform to Create Drug
Part 2 of Pharmaceutical Technology Post-Webinar Series
Learn how ApiJect built its Technology Platform around BFS to create innovative drug delivery systems for the prefilled syringe market and other sterile liquid pharmaceutical delivery formats.
BFS and Prefilled Syringes: A Solution for Complex Formulations
Part 1 of Pharmaceutical Technology Post-Webinar Series
Many countries, including the US, lack the necessary surge capacity to reliably fill-finish and deliver billions of incremental doses of injectable drugs and vaccines during bio-emergencies.
Special Feature: PFS & Parenteral Manufacturing: How COVID-19 Changed the Market
Drug Development & Delivery, Issue: May 2021
Worldwide, the parenteral market is seeing greater emphasis on patient safety. This is driving a strong trend toward unit-dose formats, including Blow-Fill-Seal prefilled syringe, which are now the fastest-growing format for injectables.
Chats with Chaudhrey: “DCAT Week 2022”, Ray Sell
Rizwan caught up with Ray for a quick preview of what ApiJect would be taking to attendees about at DCAT Week which runs March 21st-24th March, New York City.
Chats with Chaudhrey: “Fareva Licensing Agreement”. Jay Walker
Rizwan chats with Jay, Executive Chairman at ApiJect, to learn more about ApiJect’s recent licensing agreement signed with Fareva to create a France-based 500M unit annual capacity for single-dose pre-filled vaccine injections.
Live with Chaudhrey: Ray Sell at INTERPHEX 2021
As Rizwan couldn’t make INTERPHEX 2021, he caught up with Ray Sell at ApiJect’s booth via Zoom from while he attended ELRIG UK Drug Discovery 2021 in Liverpool.
Chats with Chaudhrey: “INTERPHEX 2021 Preview”, Josh Myers
Rizwan chats with Josh last week to learn what ApiJect was doing at INTERPHEX 2021. Learn about our Technology Platform that brings together aseptic BFS with connectable components to create high-quality prefilled drug delivery systems.
Chats with Chaudhrey: “Syringe Reuse”, Edward Kelley, PhD
Interesting chat with Edward Kelley, Chief Health Officer, ApiJect, and formerly the Head, Strategic Programs, at the World Health Organization about syringe reuse, the causes, impact, and how to help overcome it.
Chats with Chaudhrey: “Blow-Fill-Seal”, Philip Leslie
Rizwan chats with Philip to learn more about the advantages and which types of products can be made using BFS.
Chats with Chaudhrey: “How to Progress your Products in BFS”, Philip Leslie
Rizwans chats with Philip to learn more about the advantages and which types of products can be made using BFS.
Join the ApiJect team! We’re always looking for passionate teammates.
We envision a world where every country can safely, locally, and cost-effectively package and deliver all of the essential injectable medicines and vaccines its citizens need to live long, healthy lives.
ApiJect Prefilled Injector
The Prefilled ApiJect Injector* is a delivery system designed to bring together the benefits of prefilled syringes with the manufacturing efficiency of multi-dose presentations. Watch the Video by clicking below.
We are ApiJect
We are a team of passionate and dedicated people. Our mission is to make injectable medicines and vaccines safe and accessible to everyone. Click the button below to watch the video.
ApiJect Prefilled Injector Assembly
The ApiJect Prefilled Injector brings together an aseptically-filled Blow-Fill-Seal (BFS) container and a pen needle-style Needle Hub* to reliably deliver injectable vaccines and medicines. Click the button below to view the video.
Fierce Pharma: “Next Supply Chain Challenge: Syringes”
An estimated 14 to 19 billion incremental injections will be required by year-end 2022 to vaccinate the world’s population against COVID-19 while supplying related boosters and adjuvants. In response, the industry is shifting billions of syringes from routine vaccinations and therapeutics to COVID, increasing existing capacity, and building new manufacturing sites for syringes. Yet COVID’s supply chain is still expected to fall short. What is the source of this looming shortage? Is “syringe nationalism” causing export embargoes? How is the industry responding? Is it a supply chain problem?
In this webinar, three experts in pharma and global health discuss potential solutions including,
INTERPHEX Live 2021: “Creating a Sustainable Public Health Supply Chain”
Industry experts share insights on how stakeholders can maintain a robust, resilient supply chain essential to global health and vaccine security, with an accelerated response time to meet the needs of current and future pandemics. The building blocks for this supply chain resiliency include tech transfer, designing for right-size capacity, improving operational efficiencies, implementing state-of-the-art technologies, and establishing regulatory and quality systems.
INTERPHEX Live 2021 Session: “Pros and Cons of Global Fill-Finish”
Responding to the COVID-19 pandemic, governments and public health agencies worldwide are developing quality vaccine programs, including local fill-finish capacity, to support global immunization. Yet even before COVID, countries were already facing increased vaccine demand due to population growth. The panel will discuss key challenges and opportunities as governments and pharmaceutical manufacturers seek to establish fill-finish facilities around the world to enable access to greater and more diversified vaccine manufacturing while improving preparedness to respond to future pandemics.
Episode 3 – “Global Supply Chain Management and Capacity Planning”
Episode 2: “The Past, Present, and Future of Advanced Aseptic Facility Design”
Episode 1: “Current Trends in Isolation Technology and Vaccine Production”
Project Profile: Technology Development Center
The ApiJect Center is focused on helping pharmaceutical companies prepare their drug product for high-speed, high-volume production in a new type of scalable prefilled syringe that is made largely using the Blow-Fill-Seal aseptic process. The ApiJect Center directly supports the future installation of large-scale commercial manufacturing for rapid deployment of critical medications.
Project Profile: Fareva
Increasing Vaccine Fill-Finish Capacity in France: 500M Unit Annual Capacity for Single-Dose Prefilled Vaccine Injectables
Project Profile: The RiteDose Corporation
In 2020, as part of the U.S. Government’s COVID-19 response, ApiJect™ entered into a long-term strategic partnership with The Ritedose Corporation (“TRC”). Together, they were able to make operational 45 million units per month of Blow-Fill-Seal fill-finish capacity for America’s COVID-19 response within 7 months out of TRC’s facility in Columbia South Carolina.
Chapter 35: How to Get Started with BFS
Chapter 32: Foil Wrap
Chapter 31: Particulate Inspection
Chapter 30: Leak Detection
Chapter 29: Punching, Engraving, and Separating
Chapter 28: BFS Machines and Support Systems
Chapter 27: Areas of a BFS Line
Chapter 26: BFS Molds
Chapter 25: Manufacturing Efficiencies
Chapter 24: CapEx and Fixed Costs
Chapter 23: Equipment
Chapter 22: Space and Utilities
Chapter 21: Filling Suite Installation
Chapter 20: Sensitivity
Chapter 19: Comparability and Feasibility Testing
Chapter 18: Cost Advantage
Chapter 17: Flexible Scaling
Chapter 16: Compact Supply Chain
Chapter 15: Breakage Resistant
Chapter 14: Transportation
Chapter 13: High Productivity
Chapter 11: Manufacturing Footprint
Chapter 10: Cost Efficiency
Chapter 9: Sterility Assurance
Chapter 8: Low Particulates
Chapter 7: Reliable Aseptic Filling
Chapter 6: Advantages of BFS
Chapter 4: Types of BFS Machines
Chapter 3: How BFS Works
Chapter 2: Blow-Fill-Seal in Pharma
Chapter 1: What is BFS?