How We Beat the Heat
in Blow-Fill-Seal

left hand static image

How We Beat the Heat
in Blow-Fill-Seal

When you’re producing a Blow-Fill-Seal (BFS) plastic container from molten resin, and filling it a second later with heat-sensitive vaccine or other sterile liquid, how do you compensate for a spread of 178 degrees Celsius between the resin and the vaccine?

Jeff Price

Principal FS Engineer

Jeff Price has 30 years of industrial, aerospace, and pharmaceutical manufacturing related experience, including 27 years specializing in all aspects of Blow-Fill-Seal aseptic liquid filling technology.

He has 7 years of experience at VP level of operations management and engineering development of a privately-owned sterile inhalation generic drug manufacturing facility utilizing Blow-Fill-Seal technology. He also authored and presented several papers on aseptic design (referenced in the 2004 FDA Aseptic Guidelines document), as well as Heat Transfer analysis of the BFS process (product temperature profile during filling process) for heat sensitive products. Mr. Price has been awarded 11 patents for innovations related to BFS processes.